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A study out of Sweden and reported in the Journal of Pain Research noted disparities in outcomes from systemic reviews of interdisciplinary pain treatment. The researchers examined the PubMed, Epistemonikos, and Cochrane Library databases, along with the International Prospective Register of...

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A new experimental drug, mavacameten, may avert heart surgery or other therapies to lessen the thickness of the septum. Findings from a clinical trial were presented at the 71st annual American College of Cardiology scientific session. Hypertrophic cardiomyopathy causes heart muscle thickening...

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In an effort to uncover empirical evidence, the National Football League is funding a trial on the efficacy of cannabis. Many professional athletes claim cannabis lessens pain after a game and accelerates recovery, but does it? Via testing and monitoring, the NFL hopes to determine the value, and...

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Chronic back pain (CBP), the most common type of chronic pain, needs better treatment. Does psychological treatment, or pain reprocessing therapy (PRT), help? “PRT seeks to promote patients’ reconceptualization of primary (nociplastic) chronic pain as a brain-generated false alarm.” A study...

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The pain of kidney stones has been likened to being “worse than childbirth” or “like a knife in the gut from the inside.” Invasive procedures to break up the stones isn’t much fun either. A new clinical trial is using ultrasound waves to break up any leftover fragments after surgery to enable...

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In an effort to uncover therapies that will modify diseases, researchers sought a better understanding of precipitating molecular events. Reporting their findings in the journal of Science Advances, the scientists found that immobilizing N-acylethanolamine acid amidase (NAAA) at a specific time...

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Researchers in an article published in this month’s BMJ ask, does medical cannabis relieve cancer or noncancer related chronic pain? They examined at around 30 trials with over 5100 patients given oral or topical medical cannabis. Results compared with placebo:

  • Noninhaled medical cannabis led to...

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Information in a preprint article, as yet not peer reviewed, aims to better understand the brain’s reward system via the nucleus accumbens (NAcc) circuits. Via fMRI, researchers compared healthy controls and patients with fibromyalgia, looking at NAcc medial prefrontal cortexes (MPFC), functional...

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In a first of its kind clinical—and randomized, double-blind, placebo-controlled—trial, migraine sufferers will be given, via a vaporizer, CBD, THC, CBD and THC, and a placebo for 4 separate migraine attacks. Participants, ages 21 to 65, will self-administer as early as possible at the start of a...

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The lamprey is an eel-like creature in which researchers have found a protein called parapinopsin. This discovery was part of the research used to determine how brain neurons work, and may be controlled. The parapinopsin inhibited neurons, and turned off brain circuits. A similar system could be...

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