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In a study published in the Journal of Clinical Psychology in Medical Settings, 135 people diagnosed with chronic migraine—aged 10 to 17 years, mostly female (79%) and mostly white (89%)—were assessed. Researchers sought to understand “predictors of improvement in headache days and migraine-related...

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The journal of Nature Biomedical Engineering features an article highlighting a blueprint to study pain and potential treatments. Because pain is unpredictable and random, it can be hard to study. Scientists have developed a prototype closed-loop brain–machine interface that “can modulate sensory...

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Which screening and diagnostic tests are ordered for a new patient with potential musculoskeletal pain? That’s the question posed in an article published in the Journal of the American Board of Family Medicine. Researchers looked at almost 12,000 initial medical encounters over 9 years that had a...

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Findings from the 2002 to 2018 National Health Interview Survey for adults aged 25 to 84 are discouraging. Pain prevalence—for headache/migraine, joint, low back, neck, facial/jaw pain—has gone up, with people reporting a 10% increase of pain in at least 1 area. That equals an additional 10.5...

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An article in JAMA Network Open asked, “Do 5 sessions of flotation restricted environmental stimulation therapy [REST] alleviate chronic pain?” Participants floated in a tank of high salt concentrated water heated to skin temperature. Exposure to stimuli—thermal, visual, acoustic, and mechanical—was...

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The lamprey is an eel-like creature in which researchers have found a protein called parapinopsin. This discovery was part of the research used to determine how brain neurons work, and may be controlled. The parapinopsin inhibited neurons, and turned off brain circuits. A similar system could be...

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Optimal treatment of rheumatoid arthritis involves more than evaluation of inflammation and disease progression. RA is one of the 50 most common diseases, affecting 1.3 million people in the US and 15 million worldwide. Evaluation and detection of RA should involve other factors that may influence...

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Along with the potential benefits of working from home, such as flexibility and the time- and cost-savings of not commuting, some people are experiencing increased back pain, wrist pain, and overuse pain. Although issues from sitting too long at a desk are not new, they are increasing along with the...

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Pain, chronic pain, anxiety, depression, opioids. A study presented at the Association of Academic Physiatrists Annual Meeting linked all of those to "the socially disadvantaged" and stated that more needs to be done to improve patient outcomes. A  lack of access to nonpharmacological therapy, such...

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Osteoarthritis, the 5th-leading cause of disability in the US, may have met its match. Paroxetine is a selective serotonin reuptake inhibitor commonly used to treat depression and a potent inhibitor of the enzyme G protein-coupled receptor kinase 2 (GRK2). Patients with either osteoarthritis (OA) or...

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