depression

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Newswise — Depression is linked to diminished activity in parts of the brain believed to regulate mood, which previous research suggests may explain why depressed persons display an lessened ability to govern their ruminative thought process.

In a new paper published online in advance of print,...

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In an article published last month in PloS One, researchers studying 155 outpatients with major depressive disorder found that “Compared with the migraine with inactive headache group and the non-migraine group, patients with migraine with active headache had significantly higher intensities of...

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Buprenorphine and methadone are the most common medications currently used to treat opioid use disorder; both, however, are also opioids and can result in unwanted side effects. Additionally, treatment with these options often must be continued for months to prevent relapse. But an experimental...

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Further confirmation of the value of an integrative approach to pain care was provided by conclusions reached in a recent study of healthcare expenditures for patients with back pain conducted by researchers from the University of Arizona School of Medicine, Tucson. The team found that patients with...

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I think we’ve been so focused on this opioid crisis that we have forgotten that these are very brittle people who have significant psychiatric co-morbidities, including depression, anxiety, sleep disorders, substance use disorders. I think that suicide is really a silent epidemic that has not been...

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A review conducted by researchers from the National Institute of Mental Health concludes that ketamine and similar drugs may offer an innovative approach to treating severe and refractory depression. Terming the potential a “paradigm shift” in depression therapy, the authors report that ketamine...

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Findings from a new study conclude that patients on long-term opioid therapy for noncancer pain and who also suffer from depression were more successful at stopping opioid use if they also adhere to a course of antidepressant medication. These patients, in turn, experienced a greater improvement in...

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I think the essence of how to move forward in treating these comorbid conditions is to become more specific in how we define depression. It’s a word that is general, has a lot of different meanings, and when you think about it from a clinical perspective, there really are many different types of...

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A study conducted by researchers from Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego offers confirmation of small study and anecdotal evidence of the efficacy of ketamine as an antidepressant. The research team examined the FDA Adverse Effect Reporting System (FAERS) for...

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Pain and depression are complex constructs that involve disease, but also patient vulnerabilities, reinforcements, and outcomes. Dr. Clark discusses the evaluation of patients from these different perspectives with the goal of developing tailored therapies that promote rehabilitation and better...

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