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Exercise Rehabilitation in Veteran Cancer Survivors is a clinical trial from the Baltimore VA Medical Center. It seeks to determine the efficacy of exercise for patients who have survived lung cancer but have neuropathic pain, a common problem after surgery and chemotherapy. “The ultimate goal of...

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An article published in the Journal of Experimental Medicine connects the dots between neuropathic pain caused by chemotherapy and normalization of cholesterol. The article states that “Neuroinflammation is a major component in the transition to and perpetuation of neuropathic pain states.” If...

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A narrative review of minocycline—a 2nd-generation, semi-synthetic tetracycline used as a broad-spectrum antibiotic with anti-inflammatory properties—was performed by researchers evaluating its effectiveness in lessening neuropathic pain. Results were published in the Journal of Pain Research. A...

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Chemotherapy-induced neuropathic pain (CINP) is seen in up to 70% of cancer patients. Unfortunately, there is no effective treatment, and CINP causes many people to terminate their chemotherapy treatments. In a study published in the Journal of Pain Research, mice were separated into 4 test groups...

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In an article in the PNAS journal, researchers report the power of 3 antibiotics against chronic pain, possibly reducing the need for opioids. The study abstract reports that “demeclocycline, chlortetracycline, and minocycline can be repurposed for treatment of neuropathic pain and potentially for...

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Neuropathic pain—from an injury or disease of the peripheral and/or somatosensory nervous system—is usually severe and chronic, resistant to treatment, and therefore challenging for clinicians attempting to help patients. Researchers noted the high impact of neuropathic pain: "Many people with...

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