abuse

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Looking at medication options for substance use disorder, there is buprenorphine which is a full mu opioid agonist and also has an affinity to the kappa receptor which is what makes it lower liability in terms of abuse. Buprenorphine has been around for a long time. In the 1980s it was an injectable...

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Researchers at University of California San Francisco have released a chilling analysis of the spread of illicitly produced fentanyl into the worldwide drug abuse marketplace. The study was undertaken in an effort to determine whether the increase in fentanyl-containing substances was more demand...

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A study of almost 23,000 patients in North Carolina who were hospitalized for infective endocarditis found that 11% could be linked to the patient’s history of drug abuse, and that the incidence of IE admissions has escalated in step with the state’s crisis of opioid abuse. According to the authors,...

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An analysis conducted by researchers at University of Pittsburgh Graduate School of Public Health concludes that rising death rates from drug overdoses in the US long precede the now notorious “opioid crisis,” and that a near perfect exponential growth curve in these rates can be tracked back to the...

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A small study conducted by researchers from the Center for Drug Use and HIV/HCV (CDUHR) at New York University concludes that managers and staff of publicly patronized business establishments can be effective first responders to incidents of opioid overdose, if they are properly trained. A prior...

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The search for a new molecule in the face of the opioid crisis may have taken a major step forward with the recent discovery of a chemical compound, AT-121, that provides analgesia without addictive potential. Mei-Chuan Ko, PhD, professor of physiology and pharmacology at the School of Medicine,...

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New research led by a team from Binghamton University, State University at New York, concludes that single-step nasal spray delivery of naloxone is the easiest and most successful route of administration for members of the general community. Naloxone, also known by the brand name Narcan®, can be...

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A new report released by the National Drug Early Warning System, Office of National Drug Control Policy, emphasizes the complexity of assessing and treating drug overdose patients who present at hospital emergency departments. The report distills findings from a study begun in 2016 of the illicit...

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New research from Johns Hopkins Bloomberg School of Public Health suggests that the effort to establish harm reduction resources to address the opioid abuse crisis could be assisted by changing the name of these locations from “safe consumption sites” to “overdose prevention sites.” A survey of a...

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Younger patients who filled a prescription for opioids when undergoing wisdom tooth extraction were 2.7 times more likely to fill at least 2 more prescriptions in the following year, according to findings from a new study conducted in association with the Michigan Opioid Prescribing and Engagement...

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