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An article published in the Journal of Experimental Medicine connects the dots between neuropathic pain caused by chemotherapy and normalization of cholesterol. The article states that “Neuroinflammation is a major component in the transition to and perpetuation of neuropathic pain states.” If...
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Chemotherapy-induced neuropathic pain (CINP) is seen in up to 70% of cancer patients. Unfortunately, there is no effective treatment, and CINP causes many people to terminate their chemotherapy treatments. In a study published in the Journal of Pain Research, mice were separated into 4 test groups...
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In a study reported in the journal BMC Infectious Diseases, researchers analyzed HIV-infected patients on antiretroviral therapy. What causes pain in this group? Participants filled out questionnaires—the Brief Pain Inventory and the Douleur Neuropathique 4 Questions form—and patient history, lab...
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In an article in the PNAS journal, researchers report the power of 3 antibiotics against chronic pain, possibly reducing the need for opioids. The study abstract reports that “demeclocycline, chlortetracycline, and minocycline can be repurposed for treatment of neuropathic pain and potentially for...
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Neuropathic pain—from an injury or disease of the peripheral and/or somatosensory nervous system—is usually severe and chronic, resistant to treatment, and therefore challenging for clinicians attempting to help patients. Researchers noted the high impact of neuropathic pain: "Many people with...
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Two scientists from the New York University College of Dentistry have received a grant of $3,900,000 to research potential targets of chronic pain. Over the next 5 years, endosomal receptors will be studied with the aim of improving the management of pain, and using fewer—or no—opioids. The...
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From the Journal of Headache and Pain.
Abstract: An increasing number of patients with chronic persistent post-traumatic headache (PPTH) after mild traumatic brain injury (MTBI) are being referred to headache or pain specialists as conventional treatment options for primary headache disorders...
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Objective: The present study assessed somatosensory changes related to trigeminal nerve damage using extensive evaluation tools and assessed the effect of such damage on the patients’ psychosocial status and quality of life compared with healthy participants.
Methods: In 37 patients with...
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Newswise — Identifying the type of pain an adult with sickle cell disease (SCD) experiences may be useful in improving treatment, according to a new study by researchers at Yale Cancer Center (YCC) and Smilow Cancer Hospital. The findings are to be presented Saturday, December 7, 2019 at the 61st Am...
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Newswise — John A. Moran Eye Center physician-researcher Paul S. Bernstein, MD, PhD, and his patients at the University of Utah played a key role in the recent discovery of the first genetic cause for a rare eye disease.
Macular telangiectasia type 2 (MacTel) affects about one in 5,000 people...