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Exercise Rehabilitation in Veteran Cancer Survivors is a clinical trial from the Baltimore VA Medical Center. It seeks to determine the efficacy of exercise for patients who have survived lung cancer but have neuropathic pain, a common problem after surgery and chemotherapy. “The ultimate goal of...

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The journal of Minimally Invasive Surgery published an article in which the researchers systematically reviewed the literature to evaluate the effectiveness of spinal cord stimulation (SCS) in multiple sclerosis (MS) patients. 373 MS patients were found after a review of 452 articles and 7 studies...

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Research published in the journal Human Movement Science examined whether those with diabetes, with or without neuropathy, would grip objects differently than healthy subjects. Those results were compared to patients with multiple sclerosis, carpal tunnel syndrome, and Parkinson’s. Highlights of...

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Research published in the journal of Neurology tested the efficacy of IV immunoglobulin (IVIG)—commonly used to treat polyneuropathies such as chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy—on idiopathic small fiber neuropathy. Participants in the study received...

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An article published in the Journal of Experimental Medicine connects the dots between neuropathic pain caused by chemotherapy and normalization of cholesterol. The article states that “Neuroinflammation is a major component in the transition to and perpetuation of neuropathic pain states.” If...

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Chemotherapy-induced neuropathic pain (CINP) is seen in up to 70% of cancer patients. Unfortunately, there is no effective treatment, and CINP causes many people to terminate their chemotherapy treatments. In a study published in the Journal of Pain Research, mice were separated into 4 test groups...

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In a study reported in the journal BMC Infectious Diseases, researchers analyzed HIV-infected patients on antiretroviral therapy. What causes pain in this group? Participants filled out questionnaires—the Brief Pain Inventory and the Douleur Neuropathique 4 Questions form—and patient history, lab...

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In an article in the PNAS journal, researchers report the power of 3 antibiotics against chronic pain, possibly reducing the need for opioids. The study abstract reports that “demeclocycline, chlortetracycline, and minocycline can be repurposed for treatment of neuropathic pain and potentially for...

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Neuropathic pain—from an injury or disease of the peripheral and/or somatosensory nervous system—is usually severe and chronic, resistant to treatment, and therefore challenging for clinicians attempting to help patients. Researchers noted the high impact of neuropathic pain: "Many people with...

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Two scientists from the New York University College of Dentistry have received a grant of $3,900,000 to research potential targets of chronic pain. Over the next 5 years, endosomal receptors will be studied with the aim of improving the management of pain, and using fewer—or no—opioids. The...

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