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An article published in the Journal of Experimental Medicine connects the dots between neuropathic pain caused by chemotherapy and normalization of cholesterol. The article states that “Neuroinflammation is a major component in the transition to and perpetuation of neuropathic pain states.” If...
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Chemotherapy-induced neuropathic pain (CINP) is seen in up to 70% of cancer patients. Unfortunately, there is no effective treatment, and CINP causes many people to terminate their chemotherapy treatments. In a study published in the Journal of Pain Research, mice were separated into 4 test groups...
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In a study reported in the journal BMC Infectious Diseases, researchers analyzed HIV-infected patients on antiretroviral therapy. What causes pain in this group? Participants filled out questionnaires—the Brief Pain Inventory and the Douleur Neuropathique 4 Questions form—and patient history, lab...
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In an article in the PNAS journal, researchers report the power of 3 antibiotics against chronic pain, possibly reducing the need for opioids. The study abstract reports that “demeclocycline, chlortetracycline, and minocycline can be repurposed for treatment of neuropathic pain and potentially for...
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Neuropathic pain—from an injury or disease of the peripheral and/or somatosensory nervous system—is usually severe and chronic, resistant to treatment, and therefore challenging for clinicians attempting to help patients. Researchers noted the high impact of neuropathic pain: "Many people with...
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Two scientists from the New York University College of Dentistry have received a grant of $3,900,000 to research potential targets of chronic pain. Over the next 5 years, endosomal receptors will be studied with the aim of improving the management of pain, and using fewer—or no—opioids. The...
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From the Journal of Headache and Pain.
Abstract: An increasing number of patients with chronic persistent post-traumatic headache (PPTH) after mild traumatic brain injury (MTBI) are being referred to headache or pain specialists as conventional treatment options for primary headache disorders...
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Newswise — Identifying the type of pain an adult with sickle cell disease (SCD) experiences may be useful in improving treatment, according to a new study by researchers at Yale Cancer Center (YCC) and Smilow Cancer Hospital. The findings are to be presented Saturday, December 7, 2019 at the 61st Am...
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Newswise — John A. Moran Eye Center physician-researcher Paul S. Bernstein, MD, PhD, and his patients at the University of Utah played a key role in the recent discovery of the first genetic cause for a rare eye disease.
Macular telangiectasia type 2 (MacTel) affects about one in 5,000 people...
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