| Article

Results of a focus group brought to light the perspectives of 29 women (mean age 46 years) experiencing urinary tract infections (UTI). The results, reported in the Journal of Urology, identified 7 themes (below) in these categories: 1) the problems with taking antibiotics and 2) resentment towards...

| Article

At the Society of Thoracic Surgeons’ 18th Annual Perioperative and Critical Care Conference, results from an examination of opioid prescribing for over 2,000 lung resection patients were presented. These patients were enrolled in an enhanced recovery after surgery (ERAS) protocol, which lead to...

| Article

In women undergoing a hysterectomy, adenomyosis is seen in anywhere from almost 9% to over 60%. Adenomyosis is defined as endometrial glands and stroma within the middle layer of the uterine wall (myometrium), and can cause heavy monthly bleeding, dysmenorrhea, dyspareunia, chronic pelvic pain, and...

| Article

A letter published in the journal of Signal Transduction and Targeted Therapy brings to light a potential new tool to combat chronic pain. Conolidine, used in traditional Chinese medicine, is a natural analgesic alkaloid that targets the atypical chemokine receptor ACKR3. Researchers say it offers...

| Article

Children are not small adults. If drugs are first tested on adults, and they usually are, how do we know how much is too much for children? An article in Statistics in Medicine brings up these important questions for discussion. In it, researchers “propose a model based on a non‐parametric...

| Article

In an article in the PNAS journal, researchers report the power of 3 antibiotics against chronic pain, possibly reducing the need for opioids. The study abstract reports that “demeclocycline, chlortetracycline, and minocycline can be repurposed for treatment of neuropathic pain and potentially for...

| Podcast

It is becoming increasingly common to hear a new analgesic drug molecule described as a “biased ligand,” being “peripherally restricted,” or as having been “engineered.” What do these terms mean? How are such drugs designed or discovered, and how do you even know that you have one when you have one...

| Article

From the FDA:

CURE ID is an internet-based repository that lets the clinical community report novel uses of existing drugs for difficult-to-treat infectious diseases through a website, a smartphone or other mobile device. The platform enables the crowdsourcing of medical information from health...

| Article

Newswise—Psychedelic drugs could be effective in treating psychiatric disorders such as depression and post-traumatic stress disorder, but medical use of these drugs is limited by the hallucinations they cause.

“What if we could redesign drugs to keep their benefits while eliminating their...

| Article

Scientists from Hong Kong Baptist University (HKBU) have developed a novel technique that can produce pure therapeutic drugs without the associated side effects.

The approach, which uses a nanostructure fabrication device, can manipulate the chirality of drug molecules by controlling the...

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