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The Journal of Oral Rehabilitation recently discussed TMJD—or temporomandibular muscle and joint disorders—which are sometimes treated with injections of botulinum toxin. Low doses for a short period of time have shown no jaw bone loss. But what if the dosage is increased and/or given for a longer...

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An article in the journal of Social Cognitive and Affective Neuroscience states that people who take over the counter acetaminophen feel less scared, less negative, and potentially more willing to do risky things. In multiple studies discussed, people were given acetaminophen or placebo, and asked...

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Newswise — ...UT Southwestern scientists have shown exactly how anesthetics attach to the GABAA receptor and alter its three-dimensional structure, and how the brain can tell the difference between anesthetics and the psychoactive drugs known as benzodiazepines – which also bind to the GABAA recepto...

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An interesting development: Artificial electronic skin that reacts to pain. Human skin—the largest sensory organ—"is indicative of health. …pin pricks are used to study the response of a nervous system to evaluate degree of paralysis from nerve damage. Artificial skin receptors that demonstrate such...

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Opioids are powerful analgesics, but unfortunately that pain relief may come with side-effects that place a heavy burden on patients. Patients may experience diminished quality of life due to opioid-induced constipation, leading to depression/anxiety, embarrassment, increased cost of healthcare...

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A study presented in Journal of Psychopharmacology examined the potential pain management abilities of lysergic acid diethylamide (LSD). The ergot alkaloid derivative was given to 24 healthy volunteers who then showed significantly higher tolerance to pain during a cold pressor test, with mild side...

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Newswise —The burden of chronic pain includes damage to mental and physical health, lower productivity, and drug addiction. Now, a study led by researchers at the Weizmann Institute of Science suggests an original approach to treating this affliction by targeting a key gateway – one that leads to...

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What’s the link between serious mental illness and pain? An article in Schizophrenia Research explored the connection using information from almost 900 people with schizophrenia, schizoaffective disorder, bipolar disorder, or major depressive disorder. Participants completed the Global Assessment...

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In research presented today by the American Chemical Society (ACS), it is stated that long term opioid use can lead to chronic inflammation and heightened pain sensitivity. Why? Study leader Cody J. Wenthur, PharmD, PhD, commented, “…we started thinking that the patient’s own immune system could be...

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There’s a new player in the multimodal, nonpharmacologic, opioid-sparing pain management arena: the antinociceptive effect of green-spectrum light exposure. This potential new tool in the fight against pain works with the knowledge that areas of affect and circadian rhythm are influenced by visually...

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