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One patient, multiple doctors, multiple medications. A study published in JAMA Network Open looked at benzodiazepines and opioid prescribing and, even when adjusted for patient characteristics and prescription dosing, a 20% higher risk of overdosing was seen. Data from over 525,000 patients was...
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A new study reported in JAMA states that the combination of older age, dementia, and polypharmacy is equaling a potential rise in overdose risk and is not helping mental status. Study researchers examined the records of over 1.1 million dementia patients, median age 83, and determined that almost 14...
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Newswise — ...UT Southwestern scientists have shown exactly how anesthetics attach to the GABAA receptor and alter its three-dimensional structure, and how the brain can tell the difference between anesthetics and the psychoactive drugs known as benzodiazepines – which also bind to the GABAA recepto...
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Benzodiazepines and ‘Z’ drugs are frequently coprescribed to pain patients. They were developed for legitimate medical needs, but unbridled success and application has led to serious problems, some of which are known. The potential extreme duration of the withdrawal syndrome, however, is virtually...
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Newswise — Babies born after being exposed to both opioids and benzodiazepines before birth are more likely to have severe drug withdrawal, requiring medications like morphine for treatment, compared to infants exposed to opioids alone, according to a Vanderbilt University Medical Center study...