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An article in the journal of Social Cognitive and Affective Neuroscience states that people who take over the counter acetaminophen feel less scared, less negative, and potentially more willing to do risky things. In multiple studies discussed, people were given acetaminophen or placebo, and asked...

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Over-the-counter analgesics are easy to access and are, for many, a way to control pain. However, a study published in the journal of Pharmacoepidemiology and Drug Safety brought to light some sobering statistics. Almost half a million suicide related cases called in to Poison Control Centers in the...

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From the European Journal of Medicinal Chemistry

Highlights:

• We describe a novel class of diethylaminocarbonyl-2-benzenesulfamide analogs to acetaminophen/paracetamol.

• Compounds, 3b and 3r, lack the hepatotoxicity present in acetaminophen/paracetamol.

• 3b and 3r maintain analgesia...

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Newswise — About 29 million Americans use over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain. Every year in the United States, NSAID use is attributed to approximately 100,000 hospitalizations and 17,000 deaths. In addition, the U.S. Food and Drug Administration recently...

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Acetaminophen has been available in the U.S. without a prescription since 1955. Concerns about its potential link to cancer come from its relationship to another drug: phenacetin. That drug, once a common treatment for headaches and other ailments, was banned by the FDA in 1983 because it caused...

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One consequence of the public health crisis of opioid abuse has been an increased interest in the practice of multimodal analgesia for postsurgical pain management. Jacques YaDeau, MD, an anesthesiologist at Hospital for Special Surgery (HSS) in New York, remarked, “How to optimize multimodal...

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