| joint dysfunction

Battery Powered Cap Targets Primary Motor Cortex

Desensitizing Brain Areas That Process Pain

Newswise — Tired of living with painful arthritic knees, 54-year-old Deborah Brown’s interest was piqued when she saw a recruitment flyer for a clinical trial on an innovative pain treatment at The University of Texas Health Science Center at Houston (UTHealth).

“My knees feel like bone on bone,” said Brown, who works at a blood donation center. “It’s a shooting pain and it has been getting worse.”

That joint pain that Brown and other osteoarthritis patients experience has been traced to a part of the brain called the primary motor cortex.

Ahn said the brain is an electrochemical organ that processes pain and that his team is trying to desensitize the areas tied to knee pain.

Study participants wear a cap powered with three AAA batteries that relays a weak current between a positive and negative electrode. There are 15, 20-minute sessions over a three-week period.

To see if the brain stimulation works, participants are asked to rate their pain on a scale of 1 to 100 before and after the treatment to complete a questionnaire. Researchers will also review medical images of the brains of participants for possible changes.

To establish the validity of the experiment, Ahn is creating a control group comprised of volunteers who do not receive enough brain stimulation to make a difference. “They’re our baseline and their scores will be compared to the people receiving full treatment,” Ahn said.

“Knee osteoarthritis pain is one of the most common pain conditions among people more than 45 years of age, and pharmacological interventions do not adequately address this common condition,” Ahn said.

To be eligible, volunteers must be 50 to 85 years of age, have no serious medical conditions (e.g., brain tumor, seizure, or stroke) and be able to attend four sessions in the Texas Medical Center. For more information, call 713-500-2179.

Said Brown, “I feel a little tingling when I wear the cap. I hope it works. I’m tired of the pain pills.”

 

Read the full press release on Newswise.

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