More than 73 million surgeries are performed in the United States each year, causing a great deal of pain. Acute postoperative pain is a serious problem for many patients. Nearly 50% of postoperative patients have moderate pain, and more than one-third suffer severe pain. There are serious consequences to unrelieved pain, both physically and psychologically. Pain can cause anxiety, stress, sleeplessness, and dissatisfaction with care. Pain also affects healing and recovery, reduces mobility, interferes with pulmonary function, and, if inadequately treated, leads to an increased risk for chronic pain. This session will cover statistics and incidence of pain in the surgical patient and components of preemptive analgesia. The management of postoperative pain will be reviewed including nonopioid, opioid, and adjuvant analgesics. Special delivery methods of pain control will also be reviewed, such as PCA, epidural, and peripheral local anesthesia infusions.