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A recent study out of England found that chronic pain—which activates microglia, and thus inflammation in the brain— could lead to dementia in older adults. Researchers say their findings suggest that such pain is biologically linked to detrimental brain changes which can eventually evolve into...

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Researchers at NYU College of Dentistry’s Pain Research Center screened 27 million compounds and identified one that reversed four types of chronic pain in animal studies. The small molecule outperformed gabapentin without bothersome side effects, making it a potential new treatment for pain.

Rea...

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Primary care providers are often the first stop for patients experiencing chronic back pain. When a provider suspects that such pain is caused by axial spondyloarthritis (SpA), the next step should be a prompt referral to a rheumatologist, with a note that the patient should be considered a high...

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Kate A. Schopmeyer, PT, DPT, CPE, is the Physical Therapy Program Coordinator, Pain Management at the San Francisco VA Healthcare System in San Francisco, CA. She works with patients with complex persistent pain conditions, and was integral in creating an accredited intensive outpatient pain...

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Researchers who examined 75 years of data pulled from 85 studies and more than 800,000 participants, determined that adults who experienced childhood trauma, including direct abuse or neglect, or indirect trauma through household dysfunction, are 45% more likely to report chronic pain. The study...

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Patients who report chronic pain often report sleep disturbances. And in a domino effect, that lack of sleep can make these patients even more sensitive to pain, referred to as CSD-induced hyperalgesia.

Scientists have long known that there is a relationship between poor sleep and pain, but weren...

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At the 48th Annual Regional Anesthesiology and Acute Pain Medicine meeting, effective pain management during breast cancer surgery was discussed. Due to breast tissue’s complex nerves, anesthesia can prove difficult. With any surgery, pain control is critical and can lower chronic pain risk. As...

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In the United States, ~18 million of the 50 million people with chronic pain are prescribed long-term opioids and are at risk of addiction or overdose. Might self-guided eHealth help? A study in the journal of PAIN describes a clinical study of 400 participants who were randomized to an as usual...

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An article published recently on JAMA Network, detailed a study of the rates of chronic pain incidence and persistence in adults in the United States.

The findings suggest that there is a high disease burden of chronic pain in the adult population of the US that results in loss of life, or loss...

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Researchers are closer to understanding how the brain processes pain. While there is still much research to be done, the preliminary data holds promise for the development of new chronic pain treatments.

Recently published in Nature Neuroscience, the research findings were funded by the National...

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