Intraoperative Methadone: Another Tool for Managing Postsurgical Pain

A study conducted by researchers from NorthShore University Health System, Evanston, Illinois, reports that patients who receive intraoperative methadone during spinal fusion surgery need lower quantities of opioids, both oral and intravenous, to manage...

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Opioid Use Disorder: Primary Care Must Improve Its Management

A study of patient outcomes in a large general healthcare system found almost 20% of patients with opioid use disorder (OUD) died at some point in the 4 years following care. The results suggest a much higher mortality risk for patients with OUD in the general care setting, compared with...

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The Dilemma of Postoperative Pain in High Risk Patients and Addiction

A news story and accompanying article appearing last week, and authored by National Public Radio correspondent Craig Lemoult, highlights the problem of postoperative pain management in high risk patient populations. The story details...

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Sex Disparity in Outcomes of Total Joint Arthroplasty?

Findings from a study conducted by a team from Rush University Medical Center, Chicago may help to explain the higher incidence of complications from total hip and knee replacement surgery in women as compared to men. The study implicates hypersensitivity to...

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Medicine Cabinet Spring Cleaning: Safe Disposal of Prescription Drugs

Coinciding with, and in support of, National Prescription Drug Take Back Day, April 29, the American Medical Association (AMA) has released new recommendations for clinicians to engage in promoting the safe use, storage, and disposal of prescription opioids. The AMA says that the new recommendations, generated by its Task Force to Reduce Opioid Abuse, are...

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A New Target for Inflammatory Bowel Disease to Aid in Treatment?

A study led by researchers from Georgia State University, in collaboration with colleagues from Emory University and University of Michigan, reports that the regulation of inflammatory bowel disease (IBD) by immune cells can be affected by a specific cytokine or small protein. Cytokine IL-36? was found to induce the development of the T helper cell Th9, which is associated with...

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