| Podcast
Ketamine, known on the street as "special K," is a dissociative anesthetic with hallucinogenic properties and is classified as a controlled substance. Its unique mechanism as an N-methyl-Daspartate (NMDA) receptor antagonist is thought to be responsible for many of the drug's most promising...
| Podcast
Patients suffering from chronic pain commonly experience comorbid problems that can further impair quality of life. These include psychological and medical comorbidities and fatigue and sleep disorders. Greater than 50% of patients with pain disorders experience sleep disturbance, with estimates as...
| Podcast
Chronic pain can lead to inactivity, functional impairments, and prolonged disability. Some of the potential secondary consequences of pain related avoidance of typical daily activities include unemployment, a loss of independence, and an increased risk of other chronic diseases including...
| Podcast
Osteoarthritis (OA) is the fastest growing major health condition with symptomatic disease affecting approximately 46 million people in the US. Hyaluronic acid gives synovial fluid the viscous quality that helps to lubricate and absorb shock. Joints affected by OA have poorer quality and less...
| Podcast
Managing risk is an essential part of medical practice, particularly in light of the reported increase in morbidity and mortality associated with the use of opioids. Recent anecdotal data indicate that as a result of the "opioid crisis," patients are being told by their prescribers that they can no...
| Podcast
Although many providers have experience in advising their patients to use topical analgesics for treatment of various types of acute and chronic pain conditions, there are new insights into just how important the skin is in evaluating and treating people with chronic pain. In this translational...
| Podcast
Controversies continue to exist regarding safe and appropriate management of people with chronic pain. The "pendulum has swung in the other direction" with respect to the utility, safety, and efficacy of the use of opioids as a key component of chronic pain treatment. It seems to be unclear to many...
| Podcast
Counterfeiting is big business. In 2012, counterfeit auto parts accounted for $4 billion in the US and $12 billion globally; electrical parts were $15 billion; personal care $4 billion; aerospace & defense accounted for 520,000 counterfeit parts in the US, and >5% of wine sold on the secondary...
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For decades, the concept of morphine equivalent daily dosage (MEDD) or some variant thereof has been routinely utilized clinically (eg, for opioid rotation) as well as in research as a dependent variable. However, recently, the concept has been demonstrated to be a scientifically invalid course...
| Podcast
The emerging role of botulinum toxins as chemical neuromodulators, specifically in the management of chronic intractable painful syndromes, will be presented. There is compelling evidence showing that toxins modulate chronic neurogenic inflammation, commonly expressed as peripheral sensitization...