Molecular Discovery May Advance Disease Prevention and Treatment

New research published this week in the journal Immunity advances our understanding of the mechanisms underlying the onset of chronic inflammation. The discovery of 2 microRNA molecules that appear to control inflammation may also enable the development of more effective treatments for the subsequent ailments, such as cancer or autoimmune disorder that often occur, especially with aging.

Previous studies have shown that chronic inflammation is linked to the development of certain conditions including diabetes, lupus, arthritis, obesity, cancer, neurodegeneration, and cardiovascular disease along with a shortened life span. Certain types of immune cells, called T follicular helper cells, are known to promote the production of antibodies that attack our own tissues and contribute to chronic inflammation. This study found that the microRNAs at issue are produced by and act to control these important cell types.

Read more about the research here.




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