The study reviewed data from 5,760 US adults now in their 70s, who had completed a national, long-term investigation of atherosclerosis. Over the course of 5 medical examinations starting in their 40s and 50s, participants were assessed for various markers of inflammation. At the 5th exam, they were categorized for degree of robustness or frailty according to scores on several attributes of health. Overall, it was found that each standard deviation of elevated inflammation in midlife was connected to a 39% greater likelihood for frailty in later life. Coauthor Jeremy Walston, MD, the Raymond and Anna Lublin Professor of Geriatric Medicine at Johns Hopkins, commented, “Stay tuned—hopefully we’ll be able to say with more accuracy in the not-too-distant future that treating chronic inflammation will reduce your risk of muscle decline and related frailty.”
Read more about the research conclusions.
The journal abstract may be read here.
Posted on April 27, 2018