Daily Dose

The Chronic Pain Connection: Analgesics Won't Pay for Sleep Debt

New research on mouse models may provide a greater understanding of the connection between pain intensity and sleep loss, a topic that...

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Treating Osteoarthritis With Fat Tissue: Therapy Reduces Inflammation

Encouraging results from a new therapeutic approach to treating bone joint conditions, including osteoarthritis and joint injury, have been reported by orthopedic physicians at Rush University Medical Center in Chicago. Lipogems®, a suction device that...

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Knee Replacement Surgery: Presurgical Opioids Worsen Pain Outcomes

On average, patients with osteoarthritis of the knee spend 13 years taking medications before undergoing total knee arthroplasty (TKA) and almost 25% of these are...

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No Consistency in Opioid Prescribing for Minor Injuries

Researchers from the Perelman School of Medicine at the University of Pennsylvania are voicing concern over disparate opioid prescribing patterns for minor injuries and the contribution of these to the public health crisis of opioid abuse and...

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Pain Catastrophizing: How Thinking Can Make it So

The impact of catastrophizing behavior on treatment outcomes for patients with chronic pain has been considered at some length in the PAINWeek curriculum. Robert Gatchel, PhD, professor of psychology at the University of Texas at Arlington, has edited one of...

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FDA to Clinicians: Acupuncture, Chiropractic Care for Pain Management

Last week, the FDA released a draft of proposed changes to its extended release and long-acting (ER/LA) opioid analgesics REMS program that for the first time advocate for the education of healthcare providers on...

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Forestalling Onset of Osteoarthritis and Joint Failure, Replacement

Maintaining sufficient levels of adenosine, a biochemical involved in human cellular function, may prevent the onset of osteoarthritis, as reported by researchers at NYU Langone Medical Center working with rodent models. According to the authors...

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Discovery May Lead to More Treatment Options for IBD

A research team led by Eóin McNamee, PhD, at University of Colorado-Anschutz Medical Campus, has identified a microRNA produced by white blood cells that can modulate the inflammasome responsible for inflammatory bowel diseases (IBD), including...

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A Novel Drug Target for Pain, Memory, and Nicotine Addiction

Researchers from Texas A&M University are seeking to develop new drugs that alter the function of nicotinic acetylcholine receptors in the brain which, if successful, may result in new treatment options for conditions that include...

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Neonatal Abstinence Syndrome: Buprenorphine Instead of Morphine

New research may change the prevailing approach to treating neonatal abstinence syndrome (NAS), according to the authors of a New England Journal of Medicine article published last week. Currently, babies born to mothers who have used opioids...

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