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Headache: A Neuropathic Pain State

Alleviating Debilitating Headaches Post Traumatic Brain Injury

From the Journal of Headache and Pain.

Abstract: An increasing number of patients with chronic persistent post-traumatic headache (PPTH) after mild traumatic brain injury (MTBI) are being referred to headache or pain specialists as conventional treatment options for primary headache disorders have not been able to adequately alleviate their debilitating headache symptoms. Evolving clinical and mechanistic evidences support... 

Introduction: Traumatic brain injury (TBI), particularly mild traumatic brain Injury (MTBI) recently received increasing attention due to the media coverage in professional athletes and recent warfare in the Middle East. The United States Center for Disease Control and Prevention (CDC) estimated the prevalence of new TBI cases in the country at over 1.7 million cases per year... 

Conclusion: ...additional research is required to further reveal the relevance and relationship between the underlying NP pathophysiology and other co-existing neurological, mood and cognitive dysfunctions. Doing so will facilitate the development of clinical evaluation guideline, and treatment modalities and algorithm based on collaborative multidisciplinary approaches to address the current gap in patient care.


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