Supported by Pernix Therapeutics
This activity is not certified for credit.
Wednesday, September 7
Patients with chronic pain can be complex and present with multiple comorbidities, including sleep disturbance and affective disorders. Longitudinal studies generally support a reciprocal relationship between sleep disturbance and pain, where poorly controlled pain can disrupt sleep, and poor sleep can exacerbate pain. Pain correlates with shorter sleep durations and worse sleep quality, and impacts mood, daily activities, relationships, quality of life, and ability to work, while sleep disturbance worsens the long-term prognosis of chronic pain, increases disability, and influences daily fluctuations in clinical pain. The interrelationship between pain and poor sleep is further impacted by the prevalence of sleep apnea in patients receiving chronic opioid therapy. Concomitant affective disorders are associated with greater pain intensity, interference with activities, and healthcare costs, and a lower likelihood of responding to treatment.
Increased opioid use among patients with sleep problems or depression lends support to the hypothesis that pain patients may be self-medicating with opioids. Accidental overdose may occur when patients attempt to relieve suffering from poorly controlled pain, depression, anxiety, or disturbed sleep.
After attending this PDM program, participants should be better able to:
Jeremy A. Adler, MS, PA-C
Jeffrey Fudin, BS, PharmD, FCCP
Jay Joshi, MD, DABA, DABA-PM, FABA-PM