Break the Mold in Pain Biology

Dual-NMR Agonists to Overcome the Current Shortfalls in the Management of Severe Acute Pain: Break the Mold in Pain Biology

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Moderate to severe acute pain is difficult to manage, with opioids often the only effective option despite their serious risks. Dual-NMR agonists, targeting both NOP and MOP receptors, are an emerging class of drugs that may deliver powerful pain relief with fewer side effects.