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The journal of Brain Science reports a study of the therapeutic potential of intrathecal and intravenous resolvin D2. Derived from docosahexaenoic acid, it is a bioactive, specialized pro-resolving mediator that reduces inflammation. Researchers examined resolvin D2’s impact on mouse models of...
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Jacques Cousteau said, “We forget that the water cycle and the life cycle are one." Water enriched with hydrogen molecules, which has had positive results when used as treatment in Alzheimer’s disease as well as depression, is now being studied for potential treatment of neurologic pain and its...
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The journal of Science reports findings from researchers accessing chemotypes from a virtual library of over 300 million molecules. The authors of the study “computationally docked each virtual molecule into the highly similar α2BAR binding site, prioritizing those that physically fit and that were...
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Pudendal neuralgia is a severely painful and debilitating neuropathic pain condition that’s often unrecognized and challenging to diagnose. Mario Castellanos, MD, is a gynecologic surgeon in Phoenix, Arizona, and an associate professor at Creighton University School of Medicine, Phoenix campus. He...
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The journal of Anesthesiology published a report on the viability of pain management medication development. Using a database and over 1600 data points, researchers analyzed variables to note the probability of “success, duration, and survivorship of pain medication development programs between...
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The journal of Plants (Basel) reported on a review of neuropathic pain and its potential alleviation due to cannabinoids. This study specifically investigated cannabinoid administration routes other than oral or inhaled. As the research into the treatment of neuropathic pain grows along with its...
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The question posed in an article published in Annals of Internal Medicine: have patients suffering from chronic noncancer pain been affected negatively by state laws curbing opioid prescribing? There have been a few overlapping laws, for prescribing caps, pill mills, enrollment, and mandatory...
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Neuropathic pain affects between 3% and 17% of the population. The journal Cureus offers a narrative review of neuropathic pain, stating that early and accurate diagnosis is paramount in improving pain control and outcomes. In this review, researchers provide updated information on neurological...
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Is greater pain reduction found with a closed-loop spinal cord stimulator (SCS) vs fixed-output, open-loop SCS system? Worldwise, 7.5% of people have low back pain, some including leg pain. JAMA Neurology reports findings from a study of participants with chronic, intractable back and leg pain for...
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After thoracic surgery, chronic neuropathic pain is common—3 months postsurgery, the rate of postthoracotomy pain syndrome (PTPS) is over half; at 6 months, 47%. Symptoms/complications include shooting/burning pain, shocking, and aching pain that can last years. A study published in the Journal of...