New research published in the journal Public Library of Science-Genetics finds that regular doses of ibuprofen extended the lifespan of multiple species, including baker’s yeast, an established aging model, as well as worms and flies. The treatment, given at doses comparable to the recommended human dose, added about 15% more to the species lives. In humans, that would be equivalent to another dozen or so years of healthy living.
The 3-year project, funded in part by the National Science Foundation and the National Institutes of Health, showed that ibuprofen interferes with the ability of yeast cells to pick up tryptophan, an amino acid found in every cell of every organism. Researchers expressed the belief that it should be possible to find other common, relatively safe drugs like ibuprofen with even better ability to extend lifespan, including in humans.
Read a news story about the study here.