Daily Dose

Special Report Offers a Summary of Perspectives on Opioid Therapy for Chronic Pain

We begin the week on The Daily Dose with a special report from the online journal STAT that reviews the dimensions of the crisis in opioid prescribing for patients with chronic pain. While not breaking new ground in the discussion, the report offers a...

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Teva Pharmaceutical Industries Product Incorporates Abuse Deterrent Technology

Teva Pharmaceutical Industries Ltd. has announced FDA approval for its new extended release hydrocodone bitartrate tablets. VANTRELATM ER incorporates a proprietary abuse...

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Discovery May Promote Better Oxycodone Prescribing Decisions

A study conducted at the Icahn School of Medicine at Mount Sinai has advanced our understanding of the mechanisms underlying oxycodone action that may be of value in the effort to...

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Promoting Nerve Regeneration Through a Well-Known Medication Class

New research on rodent models undertaken by scientists from the US and Canada has discovered that blocking a specific molecular signaling pathway can promote sensory neuron growth and prevent or reverse peripheral neuropathy. Building on previous research...

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Synthesized Steroid Successfully Prevents Toxin Accumulation in Parkinson's Disease Animal Model

Results from a preclinical study conducted at Georgetown University Medical Center show that a synthesized steroid called squalamine was effective in animal models in preventing accumulation of a protein that causes Parkinson's disease. The synthesized compound mimics...

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Comprehensive Survey on Marijuana as Pain Therapy Details Risks, Benefits, and the Unknown

Described by the authors as among the most comprehensive efforts yet undertaken, a new report from the National Academies of Sciences, Engineering and Medicine offers a review of scientific research on the health impacts of cannabis and cannabis-related products. More than 10,000 scientific abstracts...

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Study Finds Even Moderate Exercise has Beneficial Impact

Results from a study conducted at University of California San Diego School of Medicine conclude that a single session of moderate exercise can stimulate the immune system to produce an anti-inflammatory response. The authors say that the...

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First Randomized Controlled Trial Shows Lasting Improvements in Pain and Pain Interference

Chair yoga may be an effective alternate therapy for older adults with lower extremity osteoarthritis, according to findings from a new study conducted by researchers from Florida State University. According to the authors, this is the first randomized controlled...

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Targeted Intervention Into the Autonomic Nervous System as a Treatment for Inflammatory Disease

Vagus nerve stimulation has been shown, in both animal studies and some human testing by private industry, to have promise as a therapeutic option for chronic inflammatory diseases including rheumatoid arthritis, irritable bowel syndrome, and Crohn's disease. But a new refinement...

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Vitamin D Important but Efficacy, Safety of Supplementation Needs Additional Research

Results from a study published this week in Scientific Reports suggest an association between vitamin D deficiency and increased incidence of chronic headache in middle aged men. The Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) was...

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