Opioid tolerance and pain hypersensitivity associated with mTOR activation

Posted on January 7, 2014

Currently, opioids are the standard treatment for chronic pain. Patients on opioids for long periods of time become desensitized to these drugs or become paradoxically hypersensitive to pain (hyperalgesia); however, the adaptive mechanisms are not well understood.
Pain / Anesthetics News From Medical News Today

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